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| 1491 | Queen Isabella funds Columbus' voyage which leads to the discovery of the New World. |
| 1772 | Sybil Ludington rides twice the distance as Paul Revere on the same night, warning, "The Redcoats are coming!" |
| 1776 | Abigail Smith Adams, First Lady (1799-1801) and mother of John Quincy Adams, writes to her husband, "Remember the Laides, and be more generous and favorable to them than your ancestors. Do not put such unlimited power into the hands of the husbands." |
| 1777 | Mary Katherine Goddard publishes the Declaration of Independence in Baltimore. |
| 1805 | Sacagawea leads Lewis and Clark to Pacific Coast , carrying baby son on her back. |
| 1840 | Esther Howland prints the first Valentine and patents the brown grocery bag. She holds 25 patents. |
| 1848 | Elizabeth Stanton, Susan B. Anthony, and Lucretia Mott found the National Suffragette Movement which leads to the Right to Vote 75 years later. |
| 1849 | Elizabeth Blackwell becomes first licensed woman to graduate from medical school. She founds the first hospital with an all female staff for women called NY Infirmary for Women and Children. |
| 1866 | Susan B. Anthony and Caroline Severance founded the Equal Rights Association. |
| 1872 | Susan B. Anthony and 27 others are arrested for voting in a Presidential election: a criminal offense for women. Her last words: "Failure is impossible." |
| 1892 | Senda Bereson Introduces basketball and in 1901 field hockey. |
| 1903 | Mme. Marie Curie wins the first of her two Nobel prizes for the discovery of radium. |
| 1908 | Mayor of Cincinnati tells the City Council no woman is physically fit to drive a car. |
| 1909 | Ella Flag Young becomes first woman superintendent of a major public school system (Chicago). |
| 1912 | Mary Dawson develops the concept of minimum wage. |
| 1920 | Women won right to vote! |
| 1925 | Miriam Ferguson becomes first woman Governor (Texas) |
| 1931 | Geraldyn Cobb becomes first woman to pass 75 exams and to be recommended to be an astronaut. |
| 1932 | Hattie Caraway becomes first woman to be elected to the Senate. |
| 1933 | Frances Perkins becomes first woman Cabinet member. |
| 1935 | Edith Wharton becomes first woman to receive Pulitzer Prize twice. |
| 1951 | Bette Nesmith Graham invents Liquid Paper and markets it herself after IBM refuses to buy it. |
| 1955 | Rosa Parks refuses to give up her seat on the bus and becomes the Mother of the Civil Rights movement. |
| 1966 | First six women qualify for US Space Program. |
| 1972 | Gloria Steinem develops first foundation for women called the Ms. Foundation for Women. |
| 1976 | Sarah Caldwell becomes the first woman to conduct at the Metropolitan Opera after Beverly Sills refuses to sing unless Caldwell conducts. |
| 1981 | Sandra Day O'Connor becomes the first woman Supreme Court Justice. Her first job offer was to be a secretary. |
| 1987 | First Congressional Resolution passes for Women's History Month. |
| 1987 | Louise Chang and Elizabeth Wilmer: two young female students who are rewarded the two top prizes in Westinghouse Science Talent Search. |
| 1988 | Jackie Joyner Kersee Wins two gold Olympic medals in 1988 Olympics despite asthma. |
| 1990 | Oprah Winfrey becomes the first woman to own and produce her own syndicated tv show. |